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New Evidence Emerges Regarding Music’s Positive Effect on Alzheimers

A recent study out of Unity Health Toronto collaboration with the University of Toronto shows that individuals with cognitive decline or initial Alzheimer’s disease can benefit from relaxing music valuable to them.

Customized, music-based therapies for Alzheimer’s patients could benefit from modifications in the brain’s neural connections linked to enhanced memory on cognitive tests.

The Journal of Alzheimer’s Disease released the findings of this multiple-level research just this week.

According to senior author and University of Toronto Professor Michael Thaut, “We have new evidence based on the brain that melody that carries personal significance for an individual, like their wedding dance music, enables neural connectivity in ways that assist with maintaining elevated degrees of functioning.”

“Dementia individuals frequently have a hard time showing improvements in their brains.” Early findings show that the authenticity of the brain has improved, allowing for more studies into the clinical uses of melodies for dementia patients – musicians as well as non-musicians,” says Thaut.

The prefrontal cortex, the mind’s control center for deep thought functions, was found to have undergone modifications in the test subjects. Exposure to autobiographically pertinent music stimulated a specific neural network – a musical network – comes from the different brain areas that displayed distinctions in stimulation after a timespan of everyday music playback, according to neuroscientists.

The scientists found additional proof of neuroplasticity in the brain’s links and white matter.

According to the study’s lead author Corinne Fischer, a medicinal associate professor at St. Michael’s Hospital in Toronto, therapies based on music may be a workable, affordable, and easily obtainable treatment for someone in the early stages of cognitive decline.

According to her, therapeutic approaches for Alzheimer’s disease have been ineffective thus far. More extensive studies are needed to clarify clinical benefits. Still, the results indicate that a personal and home-based technique to streaming music might also be advantageous and have a durable impact on the mind for many years to come.

All test subjects (eight non-musicians and six musicians) participated in the research by listening for one hour each day for three weeks to a catalog of music that was both personal and relatable. For this study, patients underwent systemic and mission functional MRI ahead of and following the listening duration.

They listened to recordings of traditional and contemporary music while doing these scans. The modern music, which they heard just an hour before the scan, was comparable but had no sentimental value for the hearers.

The auditory cortex was the most active area of the brain once subjects paid attention to the new releases. When listening to familiar music, they activated deep-encoded connections to the prefrontal cortex, a clear indicator of executive cognitive activity.

Subcortical regions of the brain, which are less affected by Alzheimer’s disease pathology, were also strongly involved in the study.

Although further study is necessary to confirm these observations, the researchers found that musicians had brain structure and function adjustment distinct from non-musicians. Those participants, regardless of their level of musicianship, benefited from repeated exposure to autobiographically relevant music.

Music is an “entry key to your remembrance, the prefrontal cortex,” suggests Thaut, regardless of whether you’ve ever played an instrument. Continue listening tong the music you’ve loved your entire life, and you’ll find your way.” Those pieces of music hold a special place in your heart. Put that to good use as a mental gym.”

Building on previous research that recognized the brain tools that encode and protect musical recollections in individuals with early cognitive deterioration, the U of T-Unity Health research manufactures on this project with the same participants.

The researchers can utilize a bigger sample size and a robust control circumstance to analyze the function of music in adjusting brain reactions and if it’s the melody or the autobiographical quantity that elicits modifications in the brain plasticity.

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The Return of the Valuable American Chestnut Tree

Renee Yates

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An aggressive fungus killed away billions of American chestnuts a hundred years ago. Scientists are now striving to bring the tree back to its former splendor after years of neglect.

Director of the American Chestnut Foundation’s restoration Sara FitzSimmons knows she won’t be able to see the final product of her efforts. Trees have a considerably longer life cycle than that.

Fitzsimmons has spent over two decades attempting to resurrect the American chestnut (Castanea dentata). The eastern USA and southern Ontario, Canada’s woodlands were initially dominated by these essential species. An invasive pathogen was mistakenly spread by imported Asian trees, mainly employed as ornamental plants and in farms over a century ago, resulting in chestnut blight exposure.

The number of chestnut trees in the United States has decreased from between three and five billion to a maximum of 435 million, a decrease of 84 percent.

The American Chestnut Foundation, for example, is working to create a new variety of chestnut trees that is immune to blight and may get reintroduced to the wild. What is the date? To have an environmental effect with millions of sprouts on the terrain, Fitzsimmons estimates that it will take between 150 and 200 years.

Humanity and their mode of living relied heavily on American chestnut trees before the blight. Farmers could feed their pigs and turkeys chestnut nuts when the trees were plentiful. In addition to gathering nuts for food and commerce, they did a lot of foraging.

They found that the trees’ wood was strong enough for use in constructions such as shingles and beams, as well as for flooring in residences, railroad ties, and telephone poles.

Better Chestnuts for the United States

Contrary to popular belief, chestnut trees aren’t extinct despite the widespread destruction. They’re not even on the endangered species list.

A protective layer of soil microorganisms keeps the blight fungus from reaching the trees’ roots. As a result, American chestnut trees have a unique ability to persist deep in the ground.

Chestnut trees now are dwarfed by their progenitors, who grew up to 100 feet tall and had trunk diameters of 10 feet or more.

For its efforts to save the American chestnut from blight, the organization uses a breeding and biotechnology-based strategy. The American Chestnut Foundation uses backcross breeding as one of its methods. Select and transfer desirable traits from one variation to another using this strategy.

The ultimate goal is to use a different species’ blight-resistance genes to improve American chestnut trees. Backcross breeding is explained by US Forest Service research ecologist Leila Pinchot, specializing in returning chestnut trees to forests.

“We want a tree that looks and acts like an American,” she explains. Therefore this is an “attempt to merge the resistance genes from the Chinese chestnut with our Chestnut.”

The tree’s survival is not only dependent on backcrossing. SUNY-ESF professor William Powell, who directs the American Chestnut Research and Restoration Project, has utilized genetic engineering to create a tree that is immune to blight.

He mixed Wheat DNA with the American chestnut DNA. Over three decades, Powell has discovered a gene from wheat capable of fighting the blight fungus. One of the best things about this gene, according to him, is that it serves as an antifungal agent.

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Indian Jungle Seeing Return of Once Extinct Cheetahs After Seven Decades

Kelly Taylor

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Since cheetahs have been extinct in India for at least seven decades, the Environment Ministry hopes to use the cheetah as a tool to help revive green areas and increase carbon capture potential as a means of dealing with climate change.

Conservationists first proposed in 2009 that cheetahs relocate from Africa to Kuno National Park in Madhya Pradesh. The ‘Action Plan for Introduction of Cheetah in India’ unveiled recently details the government’s action plan.

“KNP’s cheetah population will be free to roam across the park and the surrounding area. In addition, the KNP cheetah population would face restriction as a metapopulation with up to three other stable Indian cheetah communities, with periodic ‘immigrants’ carried in from Africa, whenever necessary,” according to Environment Minister Bhupender Yadav’s Action Plan,

An essential first plan is to create breeding colonies across their ancestral homeland and regulate them as one metapopulation.

“Using the cheetah as an amiable flagship and blanket lifeforms to seek resources for the rehabilitation of forested areas and grassland frameworks that will support biodiversity and ecosystems from these natural systems” and “To help boost India’s potential to mitigate climate change via ecosystem recovery exercises in cheetah wildlife reserves and therefore play a role to international climate mitigation objectives” are two of the document’s other priorities.

As a direct consequence of the resulting possibility for eco-development and eco-tourism, the Ministry of Environment, Forest, and Climate Change intends to improve the livelihoods of local communities and to handle any disturbance by a cheetah or other species with the help of the local population.

Importation of 12 to 14 cheetahs (8-10 males and 4-6 females) from South Africa/Namibia/other African nations would set up a new cheetah community during the first five years of the project and then as needed.

The cheetah introduction effort will be supported financially and administratively by the National Tiger Conservation Authority (NTCA). A separate budget has been set aside for Project Cheetah as part of the overall Centrally Sponsored Scheme of Project Tiger (CSS-PT) of the Indian government.

“The Central and State governments must promise a long-term (at least 25 years) Cheetah Program encompassing monetary, education and training pledges to comply to the Action Plan. There should be cheetah protection in the NTCA’s mandate and the Forest Ministry’s Project Tiger financing.

To accommodate reasonable modifications in the relocation and habitat development plans during execution and subsequent monitoring, financial obligations need to be fluid, “the previously cited piece of writing.

In addition, success criteria (for the project) and an alternative plan are under discussion in the Action Plan.

Cheetah reintroduction should be reconsidered if the new animals do not live or reproduce within five years, according to the report.

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An Breakthrough Eye Drop Prescription For Aging Vision Gets FDA Approval

Renee Yates

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For the longest time, anyone who wanted to recover clarity in their eyesight for reading had to do one of two things: either they started using reading glasses and contact lenses or they got eye surgery to restore the eye lens. Now, with the first government approval for release, there is now an eyedrop prescription that can be used instead, providing temporary clarity to the eye for reading without the inconvenience of glasses or contact lenses as well as the risk of surgery.

Given a market name of “Vuity,” and specifically intended for eye vision cases of presbyopia, the prescription will go into full production and can be obtained from any major pharmacy at a doctor’s direction.

A presbyopia condition is fairly easy to confirm with a doctor’s eye exam, and it’s not unique. Well over 128 million Americans have it; the number represents close to half of the adults in the country. The access to Vuity is a first, as literally the vision issue of presbyopia has never been treated by a medical solution before. Some might think it’s simply a costly approach to convenience, but anyone who has worn glasses or contact lenses knows how limiting they can be throughout the day when trying to be active or moving around and then having to fish for glasses to read something or prepare lenses every morning.

Presbyopia generally affects folks after age 40, often being associated with age-related vision degeneration. Folks start off with basic reading glasses and, over time, find themselves progressing to stronger and stronger vision tools to see detail up close. The Vuity product has received significant raves from experts and Optometry associations nationwide, and it is expected to be a major ground-breaker in terms of functional vision restoration.

Vuity is only available through prescription for the foreseeable future and will not be available through any over-the-counter channels. Anyone selling it as such is likely offering a fraudulent version or blackmarket product and should be avoided, including online discounters. Vuity as authorized is extremely effective at helping the eye pupil adjust to improve focus and sight clarity up close. That said, the product will be new, and will likely produce measurable trends of side effects over 2022 as it sees broader use and application. In short, folks should not expect it to be a “perfect” solution, but it does provide a daily replacement for glasses and lenses without affecting long-distance vision, such as when driving.

A typical dosage regimen involves a single drop in each eye, which provides the expected clarity benefit for the majority of the working day. The most common side effect is eye redness or a mild headache in test patients. Cost-wise, patients can expect a charge of approximately $75-90 per month for a 30-day prescription. Whether that’s addressed by one’s health insurance will depend on their specific plan versus what is out of pocket.

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Habitat for Humanity’s First 3D Printed Home

Kelly Taylor

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Habitat for Humanity is famous for providing housing to needy families in cities all over the U.S. However, the non-profit now goes down in history as being the first charity organization to build and give away a 3-D printed home for a family in need as well.

In most cases, Habitat for Humanity homes are built with a preset plan and design, either already designated by the organization or provided by a local, donating builder-partner. However, for one Virginia family, they are the recipients of a full fully tech-designed home, with every major component designed and then crafted with 3-D printing. And unlike what people see in videos crafting plastic parts, the home that was built looks like a real home!

Similar to other skills involved, Habitat for Humanity worked with a partner to develop the 3-D plan to be used for the expected home. That partner, Alquist, had a deep level of experience already working as a 3-D printing business, and the partner managed all of the design and print production to make the components of the house possible.

The size of the home built is modest. The total dimensions add up to 1,200 square feet, provides for a total of three bedrooms with two complete bathrooms and material worked with involved concrete. The total build duration for the home plan took basically a half day, 12 hours, shaving off at least a month from a typical regular home build.

April Stringfield ended up being the lucky candidate that won the ability to buy the home from Habitat at a significant discount versus what it would have cost her in the regular market. Without Habitat’s help, Stringfield would not likely have been able to be a homeowner, which is the goal of the program helping families in need. Instead, April Stringfield and her teen son will have their own new home through the holidays instead of living in an apartment.

Stringfield commitment and “purchase” followed an age-old barter method in which her work time calculated up to a purchase value to buy the home being built. This followed Habitat for Humanity’s set program that candidate families engage in, commit their work time, have good credit and keep it good without any new issues, and qualify as low to moderate income in their earning power. For Stringfield, all the time and energy was worth it; she has a new home with a backyard, her son now has roots and a place where they can finally have a puppy, and Stringfield now feels connected to her community. In short, April Stringfield and her son are now engaged with what is becoming the elusive American Dream.

Being concrete, the home will likely stand up far better to the weather, elements and natural disasters, and Stringfield also gets a dedicated 3-D printer with the home so she can fabricate additional parts as she needs to for replacement and maintenance.

Habitat for Humanity expects the new approach to home building will continue in their projects, both due to efficiency as well as taking advantage of newer technology to build families more durable homes.

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Saving Three Pigs From A Pen That Kept Flooding

Renee Yates

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Pigs don’t necessarily get to enjoy anything remotely close to a high life. They are relegated to pits or pens, they often wallow in mud, and the food they eat tends to be garbage from humans or other animals. However, there is even a cruelty level for pigs, it turns out. A countryside owner had for years kept three pigs in a pen in the woods near his house. Unfortunately, not only were the animals exposed to the elements the whole time, they were also subjected to periodic flooding of their pen.

The local People for the Ethical Treatment of Animals chapter, or PETA, had regularly visited the pen and provided better food and straw for the animals to sleep on, but there was only so much they could do that wouldn’t end up being washed away when the local waters rose and reached the pig pen. Finally, things got to the point that the local chapter management decided to have a talk with the pigs’ owner and see if there was something they could do to take over ownership of the animals. Unlike the myths of PETA being aggressive and opting for illegal tactics, the local chapter was committed to addressing the challenge legally. Fortunately, it worked out pretty well as the pigs’ owner decided to let PETA have the pigs altogether.

The PETA chapter wasted little time rescuing the flooded pigs. All three of them were rounded up, crated and trucked over to a partner sanctuary in North Carolina. The owner was probably surprised how fast the PETA crew was able to pack everything up before he could change his mind, but they weren’t going to stick around to see if that happened. The pigs were safe and sound at their new home, the Blind Spot Animal Sanctuary & Rescue, well before the end of the day.

No one can argue that animals don’t have behavior impacts from the way they are treated, and that applies even to pigs. The three animals gingerly sniffed and explored their new area, clumping together for safety. But, soon enough, they figured out the open field area is theirs, and they were off and running chasing food as well as dunking themselves in a small pool. The simple fact that they have room to spread out and not be saturated in water was a huge improvement.

And, according to the local PETA chapter responsible for the rescue, the three pigs are doing just fine and clearly far happier in their new home versus the old one.

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