Amazing
Gene Therapy Eyedrops Bring Hope to a Teen with Rare Genetic Condition

Imagine living with blurry vision, unable to see the world clearly. For 14-year-old Antonio, this was his reality due to a rare genetic condition called dystrophic epidermolysis bullosa. This condition not only caused painful blisters all over his body but also clouded his eyes with scarring, severely impairing his vision. But thanks to a groundbreaking treatment, Antonio’s sight has been restored, bringing hope not only to him but to millions of others with similar eye diseases.
Dr. Alfonoso Sabater, a skilled and compassionate doctor, treated Antonio using innovative gene therapy eyedrops. Before the treatment, Antonio’s eyes were covered in cloudy scars, making it difficult for him to see clearly. Dr. Sabater decided to adapt a gene therapy gel that had shown promising results in treating Antonio’s skin lesions, hoping it could be reformulated to help his eyes.
The treatment, known as Vyjuvek, utilizes an inactivated herpes simplex virus to deliver working copies of a gene that produces a protein called collagen 7. This protein plays a crucial role in maintaining the structure of both the skin and the corneas of the eyes. By delivering the functional gene through eyedrops, the therapy aimed to repair the damage caused by the genetic mutation responsible for Antonio’s condition.
After rigorous testing and obtaining necessary approvals, Antonio underwent surgery on his right eye, followed by regular treatment with the gene therapy eyedrops. Remarkably, his eye recovered from the surgery without scarring, and his vision showed significant improvement each month. Recently, doctors measured his vision at an impressive 20/25 in his right eye.
Buoyed by the success, Dr. Sabater began treating Antonio’s left eye, which had even more scar tissue. Encouragingly, this eye also displayed steady improvement, measuring close to 20/50 – a substantial leap from its previous state. For Antonio, this means a world of difference. He can now engage in activities he had longed for, such as playing video games with his friends, and he feels safer when moving around independently.
Antonio’s journey to restored sight was not an easy one. It took a dedicated team of researchers, doctors, and the support of drugmaker Krystal Biotech to develop and refine the gene therapy eyedrops. The process involved two years of research and testing in mice, followed by approvals from regulatory authorities and hospital review boards.
Dr. Sabater’s unwavering commitment to finding a solution for Antonio and other patients like him drove the team’s efforts. His persistence paid off, not just for Antonio but also for the countless others who may benefit from this groundbreaking treatment in the future.
Antonio’s mother, Yunielkys Carvajal, expressed her gratitude in an emotional interview. She praised Dr. Sabater as not just an exceptional doctor but also a kind and caring human being who provided hope when all seemed lost. When they first arrived from Cuba, Antonio’s condition worsened despite surgery to remove the scars. However, Dr. Sabater reassured the family that he would continue seeking a solution – a promise he ultimately fulfilled.
The successful use of gene therapy eyedrops in restoring Antonio’s sight represents a major breakthrough in the field of medical science. It opens the door to new possibilities for treating other eye diseases, potentially bringing hope and healing to millions of people worldwide.
Amazing
Mother and Daughter Graduate Nursing School Side by Side—Two Years After Mom Donated Kidney to Save Her Life
In a story of grit, love, and second chances, a mother and daughter crossed the graduation stage together this spring—just two years after one saved the other’s life.
Ambrealle Brown, 34, dreamed of becoming a nurse. But that dream came to a halt in 2016 when she was diagnosed with Focal Segmental Glomerulosclerosis (FSGS), a rare and progressive kidney disease that forced her to leave school and rely on daily dialysis treatments lasting up to 13 hours.
As her condition worsened, Brown’s optimism faded. She was exhausted—physically and emotionally. The long wait for a transplant weighed heavily on her, and hope felt increasingly out of reach.
But her mother, Nija Butler, wasn’t ready to let her daughter give up. Although doctors initially said she likely wasn’t a donor match, Butler quietly went in for testing. She didn’t tell her daughter—she didn’t want to raise hopes unless it was certain. Then came the call: Brown had a match.
“She told me she was getting a kidney,” Butler recalled. “And I told her, ‘It’s me.’”
In March 2023, surgeons at Tulane University performed Louisiana’s first-ever robotic kidney transplant, using a minimally invasive technique that helped speed recovery for both women. With her new kidney and a renewed lease on life, Brown returned to nursing school. Inspired by her daughter’s determination, Butler decided to join her.
For the next 16 months, they studied side by side, pushing each other through the grueling demands of their program at Baton Rouge General School of Nursing. And in April, they both graduated—together.
“I couldn’t have done it without her,” Brown said. “Nursing school is hard, and having her by my side made all the difference.”
Brown is now set to begin work in a burns intensive care unit. Butler, 48, will continue her work in psychiatric care.
The two women hope their story encourages others to never lose hope—and to consider the lifesaving power of organ donation.
“As parents, we always say we’d do anything for our children,” Butler said. “And I meant it—with all my heart.”
Amazing
Scientists Reveal ‘Olo’: A Never-Before-Seen Color Created with Precision Laser Tech
In a stunning leap forward for vision science, researchers have unveiled a color no human has ever seen before. The new hue—named olo—is described as an intensely saturated blue-green that falls outside the boundaries of the natural human color spectrum.
Published in Science Advances, the study comes from a collaboration between scientists at the University of California, Berkeley, and the University of Washington. At the heart of the discovery is a new experimental tool dubbed Oz, a laser-based system that allows researchers to stimulate individual photoreceptors in the human retina with unprecedented precision.
“The Oz system represents a new experimental platform in vision science,” the study states. It works by isolating and activating just one type of cone cell—specifically, the M cones responsible for detecting green light—while bypassing the other two (S and L cones, which are sensitive to blue and red light, respectively). This kind of targeted stimulation isn’t possible under natural viewing conditions, where any light usually activates multiple types of cones at once.
In controlled experiments using laser light directed into the eyes of five participants—all with normal color vision—scientists were able to generate a perceptual experience unlike anything in nature. By activating only the M cones, participants reported seeing a blue-green shade that felt completely novel and extraordinarily vivid.
“By activating only the M cones, we elicited a color beyond the natural human gamut,” the researchers wrote. They described olo as a color of “unprecedented saturation.”
This discovery doesn’t just expand our understanding of color—it could also have practical implications. The Oz platform may pave the way for more advanced research into visual processing, new treatments or diagnostic tools for color blindness, and potentially even new types of displays capable of showing colors previously thought impossible to reproduce.
As the study concludes, “This new class of programmable platform will enable diverse new experiments,” including deeper exploration into how flexible and adaptable human color perception really is.
With olo, the boundaries of the visible world just got a little wider.
Amazing
From Wheels to Wonder: Paralysed Skater Transforms Old Boards into Bold Sculptures
When Nick Harding lost the ability to skateboard, he never imagined he’d find a new way to stay connected to his lifelong passion — through art.
In 2019, Nick was suddenly paralysed by Guillain-Barré syndrome (GBS), a rare auto-immune condition where the immune system attacks the nervous system. What started as a sore hamstring quickly escalated into a medical emergency. Within an hour of arriving at the hospital, he was on life support. He spent 13 weeks in intensive care at Southmead Hospital in Bristol and seven months in recovery, relearning how to walk and use his arms.
“Skating has always been a huge part of my life,” Nick said. “Having an outlet for that desire to play with my favourite toy is what brought the sculptures about.”
With his old decks stacked in a corner and his body still rebuilding strength, Nick began experimenting. His early attempts to make practical items were shaky — his hands lacked coordination — so instead, he focused on creating something beautiful. With no prior carpentry experience, he turned to YouTube tutorials, teaching himself to shape, sand, and finish colorful, psychedelic forms from the layered wood of worn-out skateboards.
The process helped rebuild his dexterity, but it also served as a mental anchor. “I just focused on doing a little bit every day,” he said. “It was the process that felt good when I was at my lowest.”
Now, Nick sells his sculptures through his Etsy shop Mobius Maples and has gained fans from around the world. His pieces — all carved from donated, broken, or retired boards — are abstract, swirling forms that capture the movement and spirit of skateboarding.
But for Nick, it’s not just about the art or even the recovery. It’s about staying connected to the Bristol skate scene that shaped him. He donates pieces to skate competitions and charity auctions and even hides small keychains around the city for his Instagram followers to find.
“It wouldn’t be anything if it was just me,” he said. “It’s also people who give me their old boards. Interacting with the art and letting me be involved with things is what’s kept it going.”
“I want it to be something that adds to the community, and I’m so grateful that I still have the opportunity to do that.”
Through creativity, community, and resilience, Nick Harding has transformed adversity into something both healing and inspiring — turning the boards that once carried him across pavement into lasting works of art.
Amazing
Community Petition Saves Wally the Beaver from Euthanasia
Wally, a beloved beaver who became a community favorite in Northern Virginia, was saved from euthanasia thanks to the efforts of thousands of supporters who rallied together through an online petition.
Wally first gained popularity at Huntley Meadows Park in Fairfax County, where locals and visitors often saw him hard at work building dams. However, wildlife officials considered euthanizing him after concerns arose over flooding and tree damage caused by his dam-building activities.
The community swiftly stepped in, launching a petition that quickly gathered over 10,000 signatures. Advocates argued that the beaver’s positive impact on the ecosystem—creating wetlands and habitats for other wildlife—far outweighed any inconveniences.
Local officials eventually agreed, opting instead for a humane relocation effort. Wally will now be safely moved to a suitable habitat rather than being euthanized.
“This shows how much our community values wildlife,” said Julie Ames, the petition’s creator. “We’re thrilled our voices were heard.”
Residents celebrated the decision, highlighting how Wally’s survival symbolizes the growing awareness of peaceful coexistence with local wildlife.
Amazing
Third Eaglet Joins Big Bear’s Beloved Bald Eagle Family
A third eaglet hatched yesterday in the much-loved bald eagle nest near Big Bear Lake, marking a delightful moment for the growing number of wildlife enthusiasts who have been closely watching the family online.
The nest, located in the San Bernardino National Forest near Big Bear, California, has been streaming live via the Friends of Big Bear Valley eagle cam. Observers were excited to witness the third chick hatch, a significant event considering that bald eagles usually lay two eggs, with three being somewhat unusual.
The parents, affectionately named Jackie and Shadow, are local celebrities among bird watchers. According to the Friends of Big Bear Valley, these parents have gained fame for their caring behavior, ensuring their chicks remain healthy and thriving despite the occasional harsh weather conditions.
“The hatch was smooth and perfectly timed,” said Sandy Steers, executive director of Friends of Big Bear Valley. “It’s heartwarming to see this family continue to flourish.”
Wildlife experts emphasize the importance of maintaining a respectful distance, reminding the public that the best way to enjoy and protect these birds is by observing remotely via the eagle cam.
Viewers can continue to monitor the eaglets’ development, celebrating each milestone as the chicks grow into young eagles over the coming weeks.
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